Mutated and/or overexpressed version of a normal gene of animal cells (the proto-oncogene) that in a dominant fashion can release the cell from normal restraints on growth, and thus alone, or in concert with other changes, convert a cell into a tumour cell.

Dictionary of molecular biology. 2004.

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  • oncogène — [ ɔ̃kɔʒɛn ] adj. • 1951; du gr. onkos « grosseur, tumeur » et gène ♦ Didact. Qui favorise le développement des tumeurs, notamment des tumeurs malignes (⇒ cancérigène). Virus oncogène. Gène oncogène ou n. m. un oncogène : gène, souvent porté par… …   Encyclopédie Universelle

  • oncogene — oncogene. См. онкоген. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • oncogene — (n.) 1969, from ONCO (Cf. onco ) + gene, from root of Gk. gignere (perf. genui) beget, from PIE *gen produce (see GENUS (Cf. genus)) …   Etymology dictionary

  • oncogene — ☆ oncogene [äŋ′kə jēn΄ ] n. [< Gr onkos, mass + GENE] any of various genes that, when activated as by radiation or a virus, may cause a normal cell to become cancerous oncogenic [äŋ′kəjen′ik] adj …   English World dictionary

  • Oncogene — For the journal, see Oncogene (journal). An oncogene is a gene that has the potential to cause cancer.[1] In tumor cells, they are often mutated or expressed at high levels.[2] An oncogene is a gene found in the chromosomes of tumor cells whose… …   Wikipedia

  • Oncogène — Les oncogènes sont une catégorie de gènes dont l expression favorise la survenue de cancers. Ce sont des gènes qui commandent la synthèse d oncoprotéines (protéines anormales stimulant la division et la différenciation cellulaire) et déclenchent… …   Wikipédia en Français

  • oncogene — /ong keuh jeen /, n. Genetics. any gene that is a causative factor in the initiation of cancerous growth. [1965 70; ONCO + GENE] * * * Gene that can cause cancer. It is a sequence of DNA that has been altered or mutated from its original form,… …   Universalium

  • oncogene — A gene that causes cells to grow in an uncontrolled (i.e. tumourous) manner. Oncogenes are mutant forms of normal functional genes (called proto oncogenes) that have a role in regulating cell proliferation. See: cellular oncogene; dominant… …   Glossary of Biotechnology

  • Oncogene — Cette page d’homonymie répertorie les différents sujets et articles partageant un même nom. Sur les autres projets Wikimedia : « oncogène », sur le Wiktionnaire (dictionnaire universel) Les oncogènes, une catégorie de gènes… …   Wikipédia en Français

  • oncogene — 1. Any of a family of genes that normally encode proteins involved in cell growth or regulation (e.g., protein kinases, GTPases, nuclear proteins, growth factors) but that may foster malignant processes if mutated or activated by contact with… …   Medical dictionary

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